Toxicity assessment of Phlogacanthus thyrsiflorus, a traditionally used anthelmintic plant of India

Abstract Background The leaves of Phlogacanthus thyrsiflorus are used as an anthelmintic remedy by the tribes upper Assam. This study evaluates its toxic effects in laboratory bred mice and rats. Mice were orally dosed for 5 days, whereas rats 28 days variations behaviour, feeding habits blood parameters recorded. vital organs processed histopathology to observe any alternations from normal architecture. Results No mortality or adverse manifested this assessment. Evaluated parameters, namely body weights relative organ weights, appeared be similar control animals. Also, haematological serum biochemical histopathological studies revealed results. Conclusions indicates that P. may not capable causing rats, hence, traditional use could continued. However, other further validate carried out.